A new approach for protein design based on the relative entropy
نویسنده
چکیده
A new effective and fast minimization approach completely based on the physical theory is proposed for protein design. The sequence space is essentially searched according to the Boltzmann distribution. In this approach, the relative entropy is used as a minimization object function. The method has been tested on an off-lattice model of proteins and the results are better than those obtained from other similar work. Therefore, it can be applied as a uniform frame for both folding and inverse folding of proteins.
منابع مشابه
Extended MULTIMOORA method based on Shannon entropy weight for materials selection
Selection of appropriate material is a crucial step in engineering design and manufacturing process. Without a systematic technique, many useful engineering materials may be ignored for selection. The category of multiple attribute decision-making (MADM) methods is an effective set of structured techniques. Having uncomplicated assumptions and mathematics, the MULTIMOORA method as an MADM appro...
متن کاملStudying Influence of Preheating Conditions on Design Parameters of Continuous Paint Cure Ovens
This paper concentrates on a new procedure which experimentally recognises gears and bearings faults of a typical gearbox system using a least square support vector machine (LSSVM). Two wavelet selection criteria Maximum Energy to Shannon Entropy ratio and Maximum Relative Wavelet Energy are used and compared to select an appropriate wavelet for feature extraction. The fault diagnosis method co...
متن کاملEntropy-based Consensus for Distributed Data Clustering
The increasingly larger scale of available data and the more restrictive concerns on their privacy are some of the challenging aspects of data mining today. In this paper, Entropy-based Consensus on Cluster Centers (EC3) is introduced for clustering in distributed systems with a consideration for confidentiality of data; i.e. it is the negotiations among local cluster centers that are used in t...
متن کاملA new hybrid method based on fuzzy Shannon’s Entropy and fuzzy COPRAS for CRM performance evaluation (Case: Mellat Bank)
Customer relationship management is a multiple perspective business paradigm which helps companies gaining competitive advantage through relationships with their customers. An integrated framework for evaluating CRM performance is an important issue which is not addressed completely in previous studies. The main purpose and the most important contribution of this study is introducing a framewor...
متن کاملSuggestion Pattern for Task-Based Curriculum design in Nursing Master’s Degree according to Aker
Introduction: The assignment-based approach is an educational strategy that emphasizes learning by doing tasks. In this approach, the learner learns how to act in different situations, and this approach teaches skills that are similar to the tasks that the learner encounters in the real world and in practice. Therefore, the purpose of this study was to design an optimal assignment-based curricu...
متن کامل